Research has suggested certain vitamin supplements do not extend life and could even lead to a premature death.
A review of 67 studies found \\\\\\\"no convincing evidence\\\\\\\" that antioxidant supplements cut the risk of dying.
Scientists at Copenhagen University said vitamins A and E could interfere with the body\\\\\\\\\\\\\\\'s natural defences.
\\\\\\\"Even more, beta-carotene, vitamin A, and vitamin E seem to increase mortality,\\\\\\\" according to the review by the respected Cochrane Collaboration.
The research involved selecting various studies from 817 on beta-carotene, vitamin A, vitamin C, vitamin E, and selenium which the team felt were the most likely to fairly reflect the impact of the supplements on reducing mortality.
It has been thought that these supplements may be able to prevent damage to the body\\\\\\\\\\\\\\\'s tissues called \\\\\\\"oxidative stress\\\\\\\" by eliminating the molecules called \\\\\\\"free radicals\\\\\\\" which are said to cause it.
This damage has been implicated in several major diseases including cancer and heart disease.
\\\\\\\\\\\\\\\'Just eat well\\\\\\\\\\\\\\\'
The trials involved 233,000 people who were either sick or were healthy and taking supplements for disease prevention.
After various factors were taken into account and a further 20 studies excluded, the researchers linked vitamin A supplements to a 16% increased risk of dying, beta-carotene to a 7% increased risk and vitamin E to a 4% increased risk.
Vitamin C did not appear to have any effect one way or the other, and the team said more work was needed into this supplement - as well as into selenium.
In conclusion, \\\\\\\"we found no evidence to support antioxidant supplements for primary or secondary prevention,\\\\\\\" they said.
It was unclear exactly why the supplements could have this effect, but the team speculated that they could interfere with how the body works: beta-carotene, for instance, is thought to change the way a body uses fats.
The Department of Health said people should try to get the vitamins they need from their diet, and avoid taking large doses of supplements - a market which is worth over £330m in the UK.
\\\\\\\"There is a need to exercise caution in the use of high doses of purified supplements of vitamins, including antioxidant vitamins, and minerals,\\\\\\\" a spokesperson said.
\\\\\\\"Their impact on long-term health may not have been fully established and they cannot be assumed to be without risk.\\\\\\\"
A \\\\\\\\\\\\\\\'stitch-up\\\\\\\\\\\\\\\'
But the Health Supplements Information Service, which is funded by the association which represents those who sell supplements, said many people were simply not able to get everything they needed from their diet.
Dr Rosemary Leonard\\\\\\\\\\\\\\\'s advice on vitamins
\\\\\\\"For the millions who are not able to do that, vitamins can be a useful supplement and they should not stop taking them,\\\\\\\" said spokeswoman Pamela Mason.
Another nutritionist who has formulated supplements described the review as a \\\\\\\"stitch-up\\\\\\\", arguing it only looked at studies which examined the effect they had on reducing mortality, rather than other advantages.
\\\\\\\"Antioxidants are not meant to be magic bullets and should not be expected to undo a lifetime of unhealthy habits,\\\\\\\" said Patrick Holford.
\\\\\\\"But when used properly, in combination with eating a healthy diet full of fruit and vegetables, getting plenty of exercise and not smoking, antioxidant supplements can play an important role in maintaining and promoting overall health.\\\\\\\"
研究表明,某些维生素的补充不能延长寿命,甚至可能导致提早死亡。
一个对67项研究的回顾并没有发现“令人信服的证据”能够说明抗氧化剂的补充能降低死亡的风险。
哥本哈根大学的科学家说维生素A和E可能涉及人体的自然防御。
据著名的Cochrane Collaboration报道:“不仅如此,过多的β -胡萝卜素、维生素A和维生素E可能增加死亡几率。”
研究结果涉及到不同类型的研究,而在其中817项,研究对象分别为β -胡萝卜素、维生素A、维生素C、维生素E和元素硒的研究中,研究队伍发现,这些元素会在很大程度上影响补充剂对降低死亡率的功效。
这些补充物被认为能消除引起“氧化应激”的“自由基”分子,从而预防对氧化应激对机体组织的损害。
这种损害已经涉及到几种包括癌症和心脏病的主要疾病中。
“只要吃得好”
这个试验涉及到233,000个病患或身体健康的人,他们都服用维生素来预防疾病。
考虑了各种因素并排除了另外20项研究后,研究者发现了补充维生素A与增加16%的死亡率,补充β -胡萝卜素与增加7%的死亡率和补充维生素E与增加4%的死亡率之间存在着联系。
维生素C从哪方面都没有出现任何影响,研究队说需要投入更多工作到这种补充物上,就像硒的研究一样。
总而言之,“我们没有发现证据支持抗氧化剂补充物有主要或次要的预防作用”,他们说。
过去还不清楚这些补充物有这些影响的确切原因,但是研究队推测它们可能涉及人体是怎样工作的:例如β -胡萝卜素,被认为是改变人体对脂肪的利用方式。
健康部门说,人们应该尝试从他们的饮食中摄取维生素,而且避免大量补充一种在英国市场上价值大于£330m的补充品。
“大剂量的纯化维生素补充剂,包括抗氧化维生素和矿物质,需要小心使用”,一位发言人说。
“它们对长期健康的影响仍不可以充分证实,而且不能假设它们没有风险。”
一句“片面之词”
但是,由那些补充剂销售代表成立的组织--(英国的)健康补充剂消息服务机构认为,很多人难以仅从饮食中摄取他们所需的所有物质。
“对那些成千上万的不能完全从食物中摄取营养素的人,维生素是一种十分有用的补充剂,而且他们不应该停止摄取它们”,女发言人Pamela Mason说。
另一位对补充剂作过系统陈述的营养师形容上述评论是片面之词,争论点在于它只注重检测对降低死亡率有影响的研究,而不是其他好处。
“抗氧化剂不是魔法球,而且不应该被期望消除终身的不健康的习惯”,Patrick Holford说。
“但是当恰当地使用,与富含水果蔬菜的健康饮食配合食用,加之大量锻炼和不吸烟,抗氧化剂补充在维持和促进整体健康方面能扮演一个重要角色。”
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维生素“可能缩短你的寿命”
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