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Coming Epidemic Of Type 2 Diabetes In Young Adults
Coming Epidemic Of Type 2 Diabetes In Young Adults
ScienceDaily (July 12, 2008) — How will the epidemic of childhood obesity today affect the future health of Americans? As concern about children’s health grows along with their waistlines, medical experts fear that the childhood obesity epidemic could lead to large numbers of younger adults developing type 2 diabetes, causing serious and lasting health complications for future generations of Americans.
In a new article, University of Michigan C.S. Mott Children’s Hospital pediatric endocrinologist Joyce Lee, M.D., M.P.H, warns that the most damaging effects of childhood obesity have yet to surface, and will likely result in an epidemic of type 2 diabetes among young adults, leading to a greater number of diabetes complications, and ultimately, lower life expectancy.
“The full impact of the childhood obesity epidemic has yet to be seen because it can take up to 10 years or longer for obese individuals to develop type 2 diabetes,” says Lee, a member of the Child Health Evaluation and Research (CHEAR) Unit at Mott. “Children who are obese today are more likely to develop type 2 diabetes as young adults.”
The longer a person has diabetes, Lee says, the more likely he or she is to develop devastating complications. Young adults with type 2 diabetes are therefore more likely to develop complications such as blindness and kidney failure during their lifetimes, and they have higher rates of diabetes complications and heart disease than older adults with type 2 diabetes.
Plus, babies born to young women with type 2 diabetes are at greater risk for obesity and type 2 diabetes, creating a vicious cycle.
“Recent studies suggest that there have been dramatic increases in type 2 diabetes among individuals in their 20s and 30s, whereas it used to be that individuals developed type 2 diabetes in their late 50s or 60s, “ notes Lee, assistant professor in the Department of Pediatrics and Communicable Diseases at the U-M Medical School. “This may be the first indication of a type 2 diabetes epidemic among young adults who were obese during childhood.”
Given the delayed negative effects of childhood obesity, Lee says that there needs to be a greater overall investment in childhood obesity, to prevent development of type 2 diabetes.
“Our society heavily invests in the treatment and management of chronic diseases like type 2 diabetes for adults. But it spends very little for the prevention and treatment of childhood obesity to stave off the onset of type 2 diabetes,” says Lee.
“If there isn’t a significant investment in obesity prevention and treatment during childhood within schools, communities, and the health care system, recent trends in childhood obesity will likely lead to increases in type 2 diabetes among young adults, resulting in even greater costs to society and the health care system.”
Lee notes that further studies are needed to learn more about how trends in childhood obesity will impact future rates and age at onset of type 2 diabetes.
These studies will help assess the future burden of disease and disability in the population, and to evaluate whether interventions in childhood can successfully prevent individuals from developing type 2 diabetes over their lifetimes.
Funding: Lee’s work on this study was supported by the U-M Clinical Sciences Scholars Program.
Reference: Archives of Pediatric & Adolescent Medicine, July 2008, Vol. 162, No. 7.
年轻人中2型糖尿病的流行即将到来
年轻人中2型糖尿病的流行即将到来
科学日报(2008年7月12日)--试问今天儿童肥胖症的流行将会如何影响未来美国人的健康?考虑到儿童的健康成长连同他们的腰围,医学专家担心儿童肥胖症的流行将会导致大量年轻人出现2型糖尿病,并由此引发美国未来几代人的严重和持久的并发症。
在一篇新文章中,密歇根州立大学C.S. Mott儿童医院的儿科内分泌专家Joyce Lee, M.D., M.P.H, 警告说,儿童肥胖症的最大危害已经浮现出来,并且可能导致2型糖尿病在年轻人中的流行,而2型糖尿病会引起更多的糖尿病并发症,最终,降低预期寿命。
“儿童肥胖症流行的全部影响仍然需要观察,因为肥胖儿童可在10年或者更长时间内发展为2型糖尿病,”Lee说,他是MOtt儿童健康评估与研究(CHEAR)单位的一员.“现在肥胖的儿童在长大成人后更可能患2型糖尿病。”
一个人患糖尿病时间越长,Lee说,他/她越有可能合并破坏性的并发症。因此,患有2型糖尿病的年轻成人在一生当中更有可能合并诸如失明和肾衰竭这些并发症,并且这些人比起年长的成人更容易得糖尿病并发症和心脏病。
另外,患有2型糖尿病的年轻女性孕育的下一代更容易罹患肥胖症和2型糖尿病,这就形成了一个恶性循环。
“最近的研究表明在20-30岁的年轻人中2型糖尿病有了引人注目的升高,然而,过去人们常常是50-60岁出现2型糖尿病,”Lee提到,他是 U-M医学院儿科和传染病系的助理教授。“这可能是2型糖尿病在儿时肥胖的年轻人中流行的第一个指标。”
考虑到儿童期糖尿病延迟的负面影响,Lee说在儿童期肥胖症方面需要大量全面的投资,用以预防2型糖尿病的进展。
“我们的社会在为成人的慢性病诸如2型糖尿病的治疗和管理上投入了很多。但是,在预防和治疗儿童期肥胖症的投入还远远不够,不能够减少2型糖尿病的发病,”Lee说到。
“在学校中、社区里和卫生保健制度中,如果在儿童期肥胖症的预防和治疗中没有足够的投入,肥胖症中最近的演变趋势将会导致2型糖尿病在年轻人中增多,这样一来会导致社会和卫生保健制度更多的花费。”
Lee注意到未来的研究需要学习更多关于这个存在于儿童期肥胖症的趋势将会如何影响后来的发病率,以及2型糖尿病的发病年龄。
这些研究有助于评估未来人群的疾病和残疾负担,有助于评估在儿童期介入干涉是否能够成功地预防2型糖尿病在其一生中发生发展。
基金:Lee的这项研究工作由 U-M Clinical Sciences Scholars Program支持
参考文献:Archives of Pediatric & Adolescent
Medicine, July 2008, Vol. 162, No. 7.
http://www.sciencedaily.com/releases/2008/07/080708193249.htm
